The opposite end of the muscle is called the origin. The immune system seems to attack the neuromuscular junctions.
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Angle of mouth and upper lip.

Insertion in anatomy. An insertion is the point at which a muscle attaches to the skin a bone or another muscle. Genetics the addition as by mutation of one or more nucleotides to a chromosome. Origin is the attachment end to the immovable bone while insertion is the attachment end to a more movable bone.
Muscular contraction produces an action or a movement of the appendage. Origin and insertion are two ends of a muscle that attach to a bone. Elevates corners of mouth and lips.
Insertions are usually connections of muscle via tendon to bone. For example one could say the wrist is distal to the elbow. Anatomy the point or mode of attachment of a skeletal muscle to the bone or other body part that it moves.
In anatomy an insertion describes the point of attachment in a muscle where more movement occurs. Anatomy muscles origin and insertion. So this is the key difference between origin and insertion.
Insertions are usually connections of muscle via tendon to bone. This may be a bone a tendon or the subcutaneous dermal connective tissue. Muscular weakness due to a malfunction of the immune system.
Conversely you can say the elbow is proximal to the wrist. The first symptom is usually ptosis drooping eyelids. The insertion is usually distal or further away while the origin is proximal or closer to the body relative to the insertion.
The insertion of a muscle is the structure that it attaches to and tends to be moved by the contraction of the muscle. Origin is closer to the centre of the body while insertion is furthest to the centre of the body. The act or process of inserting.
The insertion attaches to the structure that will be moved by the contraction of the muscle. Weakness in the jaw muscle will continue to the point where the patient cannot move their jaw. Insert insertion the latin elements in and serere to join plant are part of insert and insertion.
The origin is the other point of attachment but it is usually more of an anchoring point than a point of movement.
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